If you’re thinking about smoothing frown lines or crow’s feet, you’ve probably heard of Botox. But two other treatments are rising in popularity: Jeuveau and Dysport. Both are FDA-approved injectable wrinkle treatments made from botulinum toxin type A. They work by relaxing the muscles that cause expression lines. But when it comes to Jeuveau vs Dysport, how do they compare? Let’s break it down with a simple, science-backed guide that’s easy to understand, and help you decide which one might be right for your skin goals.
What Are Jeuveau and Dysport?
Jeuveau, also known as prabotulinumtoxinA and Dysport, abobotulinumtoxinA are part of the same family of wrinkle relaxers, called neuromodulators. These are treatments that temporarily block signals between nerves and muscles. And this can be helpful for people wanting to remove wrinkles they already see, and in some cases, as a preventative anti-aging treatment. This works by preventing your facial muscles from contracting as strongly, so that your skin over those muscles looks smoother.
Here’s how they’re alike:
- Both use botulinum toxin type A
- Both are FDA-approved for glabellar lines (the “11s” between your eyebrows)
- Both start working within a few days
- Both last around 3–4 months on average
- Both are safe and effective when used properly
But they’re not exactly the same. So let’s talk about the differences and what could potentially impact your choice.
Jeuveau vs Dysport A Quick Look At Their Differences
| Feature | Jeuveau | Dysport |
|---|---|---|
| FDA Approval | 2019 (cosmetic use only) | 2009 (cosmetic & medical use) |
| Type of Toxin | PrabotulinumtoxinA | AbobotulinumtoxinA |
| Dosing Units | Same as Botox (1:1 conversion) | More diluted – ~2.5–3 units per Botox unit |
| Onset Time | ~2–3 days | Often faster – some see results in 1–2 days |
| Duration of Effect | 3–4 months (up to 6 months in high dose) | 3–4 months (may vary based on area/dose) |
| Diffusion/Spread | Precise – stays localized | May diffuse more widely |
| Cost per Unit | ~20–25% less than Botox | May be slightly less per unit, but uses more |
| Focus | Aesthetic-only | Aesthetic + medical uses |
More Specifically, What Makes Jeuveau Unique?
It Is A Cosmetic-Only Formula
Jeuveau is the only neuromodulator approved solely for aesthetic use. It was designed specifically for smoothing wrinkles and isn’t used for medical conditions like migraines or muscle spasms.
Cost-Saving Potential
Because it’s only made for beauty, Jeuveau is typically 20–25% less expensive than Botox, and can be cost-competitive with Dysport depending on how much is used. Additionally, Jeuveau’s potency and usage rate are on par with Botox, which is higher than Dysport. So you can get more bang for your buck.
High-Purity Manufacturing
Jeuveau uses a “Hi-Pure” process that yields a highly purified product. This might help reduce the risk of developing resistance to the treatment over time, which could make it less effective in the long run. It is important to mention that this is not a common side effect with any of the neuromodulators.
And What Makes Dysport Stand Out?
Fast Results
Dysport may kick in a little faster compared to Jeuveau. Some users notice smoother skin in just 24 to 48 hours. Alternatively, Jeuveau begins to work in 2–3 days. While they’re pretty close, Dysport has the edge if you are looking for fast results.
Wider Spread (Good or Bad?)
Dysport’s formula tends to spread more under the skin, which can be helpful in larger areas like the forehead. But it also means more caution is needed near delicate areas (like around the eyes), where precision is key. This is something your medical provider will be knowledgeable about and will help you make the best decision for you.
Medical Uses
Dysport is also used for conditions like cervical dystonia and muscle spasms, so it may be chosen for patients who need both cosmetic and therapeutic benefits.
Jeuveau vs Dysport: Which One Works Better?
From a science perspective, both are effective for smoothing wrinkles. They both have strong clinical research backing them. Both offer similar improvements in wrinkle severity, strong safety evidence, and high patient satisfaction rates. One consideration that could sway your decision could be your age and the reason for the treatments. One study found that people in their 20s-30s responded especially well to Jeuveau, with 97% reporting visible improvement after just one treatment.
So if you’re starting Botox alternatives early for preventative aging, Jeuveau may give you more bang for your buck and satisfaction. Comparatively, Dysport is often used by patients who’ve had previous treatments and want broader-area correction, like across the entire forehead.
Treatments with both Jeuveau and Dysport lasted roughly 3-4 months. and they shared similar side effects. Most side effects are mild and temporary, lasting just a few days. Serious complications are rare when treatments are done by trained professionals.
Final Thoughts: Jeuveau vs Dysport
So, which should you choose?
| Choose Jeuveau if… | Choose Dysport if… |
|---|---|
| You want a beauty-focused product | You want fast results in large areas |
| You’re cost-conscious | You’re already used to Dysport |
| You’re in your 20s or 30s and starting early | You’re treating both wrinkles and a medical condition |
| You prefer a product with fewer additives | You need diffusion across a broad area |
The best choice often comes down to your provider’s recommendation, your goals, and your budget.
References
Beer, K.R., Shamban, A.T., Avelar, R.L., Gross, J.E., & Jonker, A. (2019). Efficacy and safety of prabotulinumtoxinA for the treatment of glabellar lines in adult subjects: results from 2 identical phase III studies. Dermatologic Surgery, 45(12), 1381-1393. DOI: 10.1097/DSS.0000000000001903